Bioinformatics and Biostatistics

Sequence Assembly:

GENXMAP & partners offer advanced sequence assembly services to transform your raw sequencing data into comprehensive, assembled genomes. Our expertise covers both known and unknown genomes, using state-of-the-art computational tools to handle even the most complex assemblies. Whether you need assembly for shotgun sequencing fragments or de novo sequencing, we ensure accurate alignment, minimizing gaps and delivering reliable results.

Genome Annotation:

Our genome annotation services help you unlock the functional potential of your DNA sequences. We accurately identify and annotate features such as introns, exons, regulatory sequences, and methylation profiles, providing you with a detailed map of your genome that’s essential for further analysis and research.

Evolutionary Biology Analysis:

We specialize in evolutionary biology analysis, offering insights into the genetic relationships between species. Our services include gene duplication analysis, horizontal gene transfer detection, and large-scale genome comparisons, which are crucial for understanding evolutionary patterns and refining taxonomic classifications.

Comparative Genomics:

GENXMAP provides comprehensive comparative genomics services, enabling you to compare gene sequences across different organisms. We help you analyze mutations, duplications, transfers, and inversions, providing a deep understanding of evolutionary complexities and aiding in your research and development projects.

Mutation Analysis:

Our mutation analysis services are designed to support cancer research and other disease studies by comparing the genomes of affected cells with normal cells. We help you identify significant genomic changes, accelerating diagnosis and aiding in the development of targeted therapies.

Bioinformatics and Transcriptomics Service

Gene Expression Analysis

GENXMAP offers gene expression analysis services that provide a detailed snapshot of your sample’s transcriptome. Our services are ideal for researchers looking to quantify changes in gene expression between different conditions, treatments, or outcomes, delivering actionable insights into cellular activity.

Single-Cell Data Analysis:

With our single-cell RNA sequencing (scRNA-seq) services, you can explore gene expression at the cellular level, uncovering variations that bulk RNA-seq might miss. Our scRNA-seq analysis services include:

- Identifying novel cell subpopulations and their unique gene expression profiles.

- Detecting altered cell states associated with drug response or survival.

- Comparing cell type composition across different conditions.

- Conducting trajectory analysis to study cell development and differentiation.

- Profiling immune receptors to understand TCR, BCR, or Immunoglobulin (Ig) clonotype compositions.

We use advanced techniques like tSNE and UMAP for dimension reduction and clustering, ensuring precise classification and comparison of cell types across your samples.

Why Choose GENXMAP?

At GENXMAP, we combine cutting-edge bioinformatics expertise with personalized service, ensuring that your projects are handled with the highest level of precision and care. Our team is dedicated to delivering customized solutions that meet your specific research needs, helping you achieve breakthrough results in genomics and transcriptomics.

For more information on how GENXMAP can support your research, please contact us

GENXMAP & partners, we are committed to advancing the statistical methodologies that drive innovation in clinical trials, from the development of new drugs and cosmetic products to epidemiological studies and the analysis of omic data (genomics, transcriptomics, proteomics, etc.). Our expertise also extends to the evaluation of new food products, focusing on their sensory and organoleptic properties. In a field where health-related challenges generate vast amounts of data, our Biostatistics services—coupled with Data Science and Artificial Intelligence—open up significant strategic opportunities and address critical challenges both now and in the future.

Our Biostatistics Services Include:

Pre-Trial Planning and Feasibility Support

- Comprehensive Statistical Consulting: We provide expert guidance from the very start, ensuring that every aspect of your study is meticulously planned to deliver accurate and reliable results.

Trial Start-Up and Planning
Early-Stage Collaboration: Our team, in partnership with expert biostatisticians, supports you right from the outset of your study. We ensure that your trial is designed for success by focusing on critical elements like sample size, hypothesis formulation, objective definition, analysis sets, and statistical models.
Risk Evaluation and Database Setup: We assist in designing a robust database and provide statistical input to risk evaluations, ensuring that all potential risks are identified and monitored from the start.

Support in Study Protocol Development

Trial Design and Sample Size Calculation: We help define the optimal trial design and calculate the appropriate sample size to ensure statistically significant results.

Hypotheses and Estimands: We assist in clearly defining hypotheses and estimands, and in setting up analysis sets and subgroups to enhance the precision of your trial outcomes.

Support During Ongoing Trials

- Centralized Statistical Monitoring: We offer continuous monitoring to ensure the integrity of your trial data and provide support for sample size re-estimation to adapt to evolving trial conditions.

- Preparation of Statistical Analysis Plan: We create detailed statistical analysis plans, along with mock tables, figures, and listings, to facilitate smooth and accurate data interpretation.

Support for Trial Analysis

- Comprehensive Study Analysis: We conduct thorough analyses of your trial data, preparing detailed statistical reports that support the clinical study report.

- Post-Hoc Analyses: Our services include post-hoc analyses to further explore and validate your trial findings, ensuring robust conclusions.

Why Choose GENXMAP for Biostatistics?

Whether you are developing a new medicinal product, expanding the indications of an existing drug, or seeking CE certification for a medical device, GENXMAP’s biostatistics team has the experience and expertise to support your project at every stage. We are ready to assist you through different phases of your trial or to provide continuous support throughout the entire study preparation and execution.

For more information on how GENXMAP can support your clinical trial or research project with our biostatistics services, please contact us.