Transcriptomics: decoding gene signatures and molecular mechanisms to unlock the secrets of your samples

Transcriptomic profiling

💡 Transcriptomics is a powerful tool in molecular biology that enables the study of gene expression in specific cells or tissues. Unlike genomics, which focuses on DNA and genetic sequences, transcriptomics analyzes messenger RNA (mRNA), capturing gene expression at a given moment. This approach is crucial for understanding how cells react to their environment, diseases, and treatments, paving the way for groundbreaking advancements in biomedical research and personalized medicine.

Why Perform Transcriptomic Profiling?

Transcriptomic profiling helps uncover biological mechanisms and identify key biomarkers. It provides the opportunity to:

✔ Analyze molecular signatures in both normal and pathological conditions (e.g., cancer, autoimmune diseases).

✔ Optimize therapeutic strategies by identifying novel drug targets.

✔ Evaluate treatment responses to determine patient efficacy or resistance to therapies.

✔ Characterize the cellular microenvironment to better understand interactions between cells and tissues.

✔ Explore metabolic pathway regulation, impacting diverse biological processes.

GENXMAP’s advanced transcriptomic profiling tools

We offer tailored solutions that combine scientific expertise with cutting-edge technologies to precisely analyze gene expression.

Global Approach – Comprehensive Transcriptome Exploration

✔ Bulk RNA-seq: Provides a broad overview of gene expression across entire samples (e.g., tissues, cell populations).

✔ Single-cell RNA-seq: Examines gene expression at the single-cell level, enabling the identification of distinct cell subpopulations with high resolution.

✔ Spatial transcriptomics: Preserves tissue architecture while capturing gene expression, allowing for spatial analysis of cellular interactions.

Targeted Approach – Precise Analysis of Genes of Interest

✔ RT-qPCR: A highly accurate method for relative gene expression quantification.

✔ Digital PCR (dPCR): Enables absolute quantification with high sensitivity, ideal for detecting rare or lowly expressed transcripts.

A Fully integrated approach for comprehensive Biomarker Analysis

GENXMAP offers the “Biomarker Xplorer” package, ensuring the rigorous validation of identified markers:

✔ Global transcriptomic analysis: Identification of key genes of interest.

✔ Bioinformatics analysis: Selection of the top 5 most relevant genetic markers.

✔ Transcriptomic validation: Confirmation via qPCR or dPCR.

✔ Proteomic validation: Verification using flow cytometry, Western blot, or ELISA.

With this integrated approach, we help accelerate biomarker discovery and validation for your research projects.

📩 Contact us to learn more about our transcriptomic solutions!🌐 Visit our website: https://www.genxmap.com/