Our ecosystem · Wet lab, analysis, R&D

Our wet-lab platforms, and the science we build on them.

GenXMap covers one continuous chain: instrument work at the bench, then integration, biomarker discovery and modelling by our computational team. The bench side runs in our Marseille laboratories and through a qualified partner network, and it is ordered on OMICS4, our production and booking site. You can stop once the data is delivered, or keep going all the way to the biology.

GenXMap brings together the OMICS4 wet-lab platforms, multi-omics and computational biology in one scientific workflow, from sample preparation and quality control through sequencing, quantitative assays and proteomics to integrated interpretation. Use a single platform, combine several, or ask GenXMap to design and run the complete study.

Three ways to work with us

Platform only

You provide the samples. We run the laboratory workflow and deliver quality-controlled primary data: QC results, sequencing files or raw measurements, processed primary data and platform-specific documentation. This is a finished deliverable, and you can take it to your own bioinformatics team.

Platform + analysis

We run the laboratory work and continue into bioinformatics, statistical analysis and biological interpretation, reported against your question rather than the instrument.

Integrated programme

We start from the biological question, define the study design, select the platforms and models, coordinate laboratory work including partner steps, and deliver one integrated interpretation. One project lead holds the documented chain from sample to report.

What we measure in Marseille

Sample preparation and QC

DNA, RNA and protein extraction; normalisation; concentration, purity, fragment-size and integrity assessment. A sample is qualified for its downstream assay before sequencing or profiling is spent on it. Accepted inputs include fresh-frozen and FFPE tissue, blood and plasma, cultured cells, tissue models and microbial samples.

Genomics

Whole-genome, whole-exome and targeted sequencing; genotyping; somatic and germline variant, copy-number and mutational-signature analysis.

Bulk transcriptomics

RNA-seq for differential expression, pathway analysis and expression signatures across conditions.

Targeted assays

qPCR, RT-qPCR and dPCR for target detection, expression measurement and genotyping; Olink proximity extension assays for targeted protein panels. Used standalone or to validate sequencing and proteomic findings.

Proteomics

Mass-spectrometry-based profiling on TIMS-TOF MS: differential protein abundance, protein signatures and pathway-level responses complementary to transcriptomics.

Metagenomics and microbiome

16S profiling for community composition, diversity and differential abundance; shotgun metagenomics for taxonomic and functional characterisation, strain-level resolution where depth supports it, and antimicrobial-resistance genes. Integrable with host molecular profiles.

Extracellular vesicles

Isolation, characterisation and molecular cargo analysis, linking intracellular transcriptomic or proteomic changes to the signals cells send out.

What we run through partners

Not every technology needs to be maintained in-house. For selected steps GenXMap works with specialist partners under its own study design, project coordination and documentation framework. The client deals with one project lead, not with a set of vendors.

Higher-resolution transcriptomics

Single-cell transcriptomics with Parean Biotechnologies; spatial transcriptomics with Explicyte, an immuno-oncology CRO.

In vitro and ex vivo models

Where a programme needs a biological system rather than a sample, GenXMap's omics are run on models from partner CROs: 3D human tissue models and oncology screening systems from CTI Biotech (Lyon); 3D skin models, precision-cut lung slices and permeation testing from PKDERM (Sophia Antipolis); human adipose tissue models from DIVA Expertise. The model, exposure design and molecular readout are planned as one study.

Complementary analytical platforms

Proteomics, Metabolomics and molecule-delivery analysis complementary to GenXMap's platform, through GCLIPS and the IHU Méditerranée Infection platforms.

The full ecosystem →

Beyond a single measurement

Three ways the platforms combine

Three resolutions, one design

Where cellular heterogeneity and tissue organisation matter, bulk RNA-seq, single-cell and spatial transcriptomics are run as one programme on one sample set: bulk shows what changed, single-cell which cells changed, spatial where in the tissue. The three are read together rather than reconciled afterwards.

See 360° transcriptomics

Multi-omics

Layers are combined when independent measurements are needed to support the same interpretation: a genetic alteration reflected in a transcriptional response, carried through to protein, and visible in a pathway or phenotype. Genomics, transcriptomics, proteomics, metabolomics, microbiome and extracellular-vesicle data can be integrated in one analysis, with batch correction across experiments and platforms.

OMICS4: the technical catalogue

Platform scope, protocols, sample requirements, turnaround times, configurations and ordering live on OMICS4, GenXMap's production and booking platform. OMICS4 runs the measurement; GenXMap designs the scientific strategy and interprets the biology.

Browse the OMICS4 catalogue

A sequencing run, a protein profile or a molecular assay is a measurement. The value is in what it means for the question.

One entity, two sites

Choose the measurement you need, or tell us the question and we will design the workflow around it.

Write to us

Questions we get asked

Can you analyse data generated elsewhere?

Yes. Existing genomic, transcriptomic, proteomic, microbiome and other datasets can be analysed on their own or integrated with new data.

Can you provide the biological model as well as the measurement?

Yes. Through partner CROs, a compound or intervention can be tested on 3D tissue, skin, lung or adipose models with the molecular readout designed in from the start.

What happens when a technology isn't available in-house?

It runs through a qualified partner, under GenXMap's study design, coordination and documentation.

Who is responsible when several platforms are involved?

One GenXMap project lead, from sample to final report.