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GENXMAP
GENXMAP
GENXMAP
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DNA Extraction & Quality Control

Each extracted DNA reveals its genetic code with rigor and precision.

Packages_OMICS-Genxmap

Reveal Gene Expression and Decode Biological Mechanisms

Extraction ADN-Genxmap

DNA Expertise Across Various Sample Types

Varied Extraction Approaches. Our team has developed and optimized protocols to tackle the unique challenges posed by different sample types.

Soil samples

  • Our methods effectively remove contaminants such as humic substances, ensuring that you receive clean DNA, free of inhibitors, suitable even for the most sensitive downstream applications.

FFPE (Formalin-Fixed, Paraffin-Embedded) Tissues

  • We use advanced techniques to extract high-quality DNA from formalin-fixed, paraffin-embedded (FFPE) tissues, overcoming challenges related to fragmentation and cross-linking.

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Applications:

  • Comprehensive profiling of microbial communities, including bacteria, archaea, fungi, viruses, and eukaryotes.

  • Functional genomics and pathway analysis.

  • Detection of rare or novel organisms.

  • Discovery of antibiotic resistance genes and other functional traits.

Microbiome Samples

  • With the diversity of microorganisms present in microbiome samples, our protocols ensure complete lysis of all cell types, providing a comprehensive DNA extraction for precise microbial analysis.

Environmental Samples (eDNA)

  • Environmental samples often contain low amounts of nucleic acids and various contaminants. Our protocols are designed to isolate environmental DNA (eDNA) even from complex matrices like sediments, soil and water, ensuring accurate and reliable results.

Bone and Teeth Samples

  • DNA extraction from bone and teeth is particularly challenging due to degradation over time and the presence of calcium-rich matrices. We use specialized demineralization and extraction techniques to obtain high-quality DNA from these resilient tissues.

Plant Samples

  • The rigid cell walls of plants and the presence of secondary metabolites can complicate DNA extraction. Our customized approaches effectively break down these barriers, ensuring the purity and integrity of DNA extracted from various plant species.

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Applications:

  • Comprehensive profiling of microbial communities, including bacteria, archaea, fungi, viruses, and eukaryotes.

  • Functional genomics and pathway analysis.

  • Detection of rare or novel organisms.

  • Discovery of antibiotic resistance genes and other functional traits.

Formalin-Fixed Biological Fluids

  • Like FFPE tissues, formalin-fixed biological fluids can pose challenges in obtaining high-quality DNA due to cross-linking. We have developed protocols that successfully extract usable DNA from these challenging samples.

Human and Animal Tissues, Body Fluids, and More...

  • We offer tailored solutions for a wide range of biological samples, ensuring optimal results.

High-quality extraction and purification of nucleic acids are essential for the success of any genomic or transcriptomic analysis. We provide specialized services covering a wide range of sample types, including tissues, body fluids, cultured cells, or more complex samples. Our expertise and advanced technologies enable us to maximize nucleic acid yield while maintaining exceptional purity, which are key factors in ensuring the reliability and accuracy of your analysis results, whether for fundamental research, clinical studies, or advanced medical applications.

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We are committed to tailoring our protocols to meet your specific needs, whether for a rare or small sample, or a complex matrix, ensuring optimal extraction compatible with the requirements of different sequencing platforms and other omics technologies.

Extracting DNA, Unlocking Potential

Services_Transcriptomiques-Genxmap

Transcriptomics

Drylab-Genxmap

Expertise & Training

Multiomics-Genxmap

Packages

Genomiques-GENXMAP

Genomics

Other solutions

Precise and advanced services, cutting-edge technologies, and reliable analyses.
Our rigorous approach ensures detailed results, essential for your scientific discoveries and clinical applications.

Service Details

    • Sample Reception and Packaging Confirmation Report

  • DNA Extraction Available By:

    • Isopropanol Precipitation

    • Columns

    • Magnetic Beads

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    Quantification and Quality Control Using the Most Suitable Methods:

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    Concentration Measurement:

    • Qubit: Precise DNA/RNA quantification, ideal for low-concentration samples.

    • Nanodrop Spectrophotometer: Fast and efficient quantification, purity assessment based on absorbance.

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    Purity Measurement:

    • Nanodrop Spectrophotometer: Measures 260/280 and 260/230 ratios to detect protein or organic contamination.

    • Agarose Gel Electrophoresis: Visualizes nucleic acids and detects contaminants.

    Fragment Size and Integrity Analysis:

    • Fragment Analyzer (Qiaxcel Connect), Bioanalyzer, and TapeStation: Provides detailed RNA and DNA integrity profiles, offering RIN and DIN values.

    Quality Control Based on PCR:

    • qPCR/dPCR: Evaluates DNA/RNA amplification efficiency.

    • RT-qPCR: Assesses RNA extraction quality by quantifying specific transcripts.

    Agarose Gel Electrophoresis:

    • Gel Visualization: A simple method for evaluating DNA/RNA degradation and contamination.

    Capillary Electrophoresis (CE):

    • CE Analysis: High-resolution fragment separation for assessing nucleic acid integrity and size.

    • Comprehensive Report Including Sample Concentration and Quality

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