Identifying and locating genetic variations within the genome by Gene Mapping.
Gene mapping involves precisely identifying and localizing genes and their variations within the genome. It plays a key role in various fields, particularly in biomedical research, where it helps identify genetic factors involved in diseases and understand their clinical implications. It is also essential in animal model studies, verifying transgene integration and determining genotype lineages. Furthermore, in gene therapy and genome editing, gene mapping validates genetic modifications induced by technologies such as CRISPR-Cas9, ensuring the precision and efficiency of genome interventions.
GENXMAP Gene Mapping Solutions to Meet Your Needs.
Targeted Genotyping via:
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Conventional PCR and qPCR – For detecting mutations (insertions/deletions/SNPs).
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Digital PCR (dPCR) – For absolute quantification and sensitive detection of rare variants.
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Sanger Sequencing – For analyzing specific sequences and validating point mutations or CRISPR-Cas9 edits.
Comprehensive Genomic Mapping via:
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Whole Genome Sequencing (WGS) – For an exhaustive analysis of all genetic variations within a cohort.
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Whole Exome Sequencing (WES) – For focusing exclusively on coding regions to identify mutations affecting proteins.
Mapping Genes, Unveiling Insights
Découverte et validation de biomarqueurs
Découvrez de nouvelles perspectives.
Chacune des ces formules incluent un process intégré et optimisé comprenant une prise en charge complète
1. Découverte et identification de biomarqueurs
Bulk RNA-sequencing ou Single Cell RNA-sequencing pour une analyse au niveau cellulaire spécifique.
2. Analyse bioinformatique et sélection des « Top marqueurs »
Analyses bioinformatiques des données de séquençage NGS et filtrage des « gènes marqueurs prioritaires ».
3. Validation transcriptomique des « Top marqueurs »
RT-qPCR et/ou PCR digitale en gouttelettes (ddPCR) des « gènes marqueurs prioritaires ».
4. Validation protéomique du « Top marker »
Immunomarquage, cytométrie, dosages ELISA.
5. Analyse biostatistique
Immunomarquage, cytométrie, dosages ELISA.
Projet personnalisé et expertise multi-omique
Options
La formule inclut plusieurs options pour répondre à vos besoins, avec la possibilité de composer votre pack d’analyse selon vos exigences.
Extraction
Extraction d’ARN avec contrôle qualité
Bulk RNA-seq
Découverte et identification de biomarqueurs par analyse Bulk RNA-seq.
Bioinformatique
Analyses bioinformatiques et accompagnement personnalisé pour identifier les marqueurs d’intérêt.
Sélection
Sélection et validation des marqueurs d’intérêt par qPCR et/ou dPCR.
Validation
Validation protéomique des marqueurs d’intérêt.
Analyses globales
Analyses bioinformatiques / biostatistiques et interprétation des résultats.
Our Go/No-Go processes allow you to track the progress of your project in real-time. At each stage, you validate the transition to the next, ensuring complete control and maximum transparency throughout the entire process.
Our optimized timelines ensure fast and efficient execution of each project while meeting your specific requirements. This system ensures proactive time management, minimizing delays and maximizing productivity to deliver results that align with your expectations.
Our tailored processes are designed to meet the unique needs of each project, offering flexibility and personalized follow-up. This system ensures rigorous control while delivering accurate results that align with your expectations.
Our detailed analyses guarantee reliable and in-depth results tailored to each study. With cutting-edge tools and proven methodologies, we provide a precise understanding of genetic data, while adhering to the highest standards of quality and scientific rigor.
GENXMAP,
your trusted partner
Efficient and traceable scientific workflows
Transparent and well-defined processes, ensuring you remain in control with complete confidence throughout your project.
