GENXMAP, your trusted partner to support you in your research.
Confocal microscopy is a cutting-edge technology that allows for capturing three-dimensional images with unparalleled precision, especially in the observation of cells and tissues labeled with specific antibodies. Thanks to its ability to eliminate out-of-focus signals, it offers enhanced resolution and increased depth of field, making it possible to study subcellular structures in detail. This tool has become indispensable in biological and medical research for visualizing protein distribution and their precise localization within complex cellular contexts, contributing to a better understanding of pathophysiological mechanisms.
In addition, GENXMAP and its partners offer advanced High Content Screening (HCS) technology. This approach combines cellular imaging with computational analysis to simultaneously assess multiple biological parameters on a large scale. Used for high-throughput studies, it enables the rapid detection of phenotypic effects in response to compounds or treatments, making it possible to identify new therapeutic targets and accelerate drug development.
Confocal Imaging, Unlocking High-Resolution Insights into Cellular Structures.
Optimized and Transparent Services
Our Go/No-Go processes allow you to track the progress of your project in real-time. At each stage, you validate the transition to the next, ensuring complete control and maximum transparency throughout the entire process.
Our optimized timelines ensure fast and efficient execution of each project while meeting your specific requirements. This system ensures proactive time management, minimizing delays and maximizing productivity to deliver results that align with your expectations.
Our tailored processes are designed to meet the unique needs of each project, offering flexibility and personalized follow-up. This system ensures rigorous control while delivering accurate results that align with your expectations.
Our detailed analyses guarantee reliable and in-depth results tailored to each study. With cutting-edge tools and proven methodologies, we provide a precise understanding of genetic data, while adhering to the highest standards of quality and scientific rigor.
Service Details
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We clearly define your scientific objectives to guide your study. Each approach is tailored to your needs to maximize the relevance and precision of the results.
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You specify the types of samples you wish to analyze (tissues, cells, environmental samples, etc.), allowing us to adapt the extraction process to ensure the quality and accuracy of the results.
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Methodology Selection:
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Based on your objectives, we provide guidance on the most suitable method for your analysis.
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Sequencing Platform Selection:
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We discuss the available options based on sample complexity and the required resolution (Illumina, MiSeq, Oxford Nanopore Technology).
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Budget and Timeline Estimation:
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Budget Validation: We provide a clear estimate of the project cost based on the chosen methodology, the number of samples, required coverage, and additional bioinformatics analyses.
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Timeline Planning: We share an estimated timeline for sample preparation, sequencing, and bioinformatics analysis, with regular checkpoints to track progress.
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Continuous Monitoring and Support:
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Ongoing Support: Once the project is launched, we support you throughout the entire process, from raw data collection to bioinformatics assistance for result interpretation, providing personalized reports and recommendations for next steps.
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Step 0 >> Sample Reception Control
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Visual evaluation of quantity and quality
Report and client decision "Go / No-Go" for proceeding with the process
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Step 1 >> Sample Preparation
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Immunostaining (mono or multi)
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Option to fix cells for later flow cytometry analysis
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Step 2 >> Data Acquisition
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BD FACSCanto II
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BD LSRFortessa
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Step 3 >> Results Delivery
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Result Formats: Provision of raw files (fcs)
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Detailed report with analysis of raw data using FlowJo (if option selected)
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FACS (Fluorescence-Activated Cell Sorting)
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Discover Our Blog
Precision, Innovation, and Reliability at the Service of Your Discoveries.
Explore our blog to learn how our cutting-edge technologies and advanced analyses are opening new perspectives in scientific research and clinical applications.
power and optical precision
Our confocal microscopy service supports diverse applications, including cellular morphology and protein interaction studies. With multi-channel and real-time imaging, we enable in-depth research on biomarker mapping, intracellular dynamics, immunology, and oncology.
High-Resolution 3D Imaging
Offers high-resolution 3D images, enabling precise observation of internal structures and interactions within cells and tissues.
Advantages:
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Captures detailed 3D images with fine resolution, allowing precise observation of internal structures of cells and tissues.
Applications:
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Cell morphology study, tissue biomarker mapping.
Optical Selection and Sectioning
Through laser scanning, confocal microscopy provides sharp, blur-free optical sections, offering a clear and detailed view of samples.
Advantages:
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Provides sharp, blur-free optical sections by eliminating background noise, enhancing image contrast.
Applications:
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Protein interaction analysis, subcellular structure detection.
Real-Time Observation
Allows real-time tracking of dynamic cellular processes, providing insights into changes and movements within living cells.
Advantages:
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Dynamic tracking of cellular processes, providing real-time data on changes and movements.
Applications:
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Tracking cellular processes such as division, migration, and response to stimuli.
Multi-Channel Imaging
The ability to image multiple targets simultaneously facilitates the study of interactions between different proteins or biomarkers in a single sample.
Advantages:
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Allows simultaneous visualization of multiple targets, aiding the study of complex interactions between biomarkers.
Applications:
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Molecular biology research, protein interaction studies.
Cell Morphological Analysis
Study cell morphology and organization—essential for research on cellular structure and function.
Key Benefits:
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🔬 High-Resolution Imaging: Enables detailed observation of cellular structures and morphological variations at a nanometric scale.
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🌈 Multicolor Visualization: Multi-channel imaging techniques allow simultaneous visualization of multiple cellular features.
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📊 Quantitative Analysis: Provides precise measurements of cell dimensions, shape, and interactions with neighboring structures.
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⏳ Dynamic Observation: Real-time monitoring of morphological processes such as cell division, apoptosis, and structural changes in live cells.
Applications:
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🧪 Fundamental Research: Investigation of core biological processes like morphogenesis and cellular differentiation.
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🎗️ Oncology: Analysis of morphological changes associated with cancer transformation and tumor progression.
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🧬 Developmental Biology: Observation of morphological modifications during cell development and maturation.
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💊 Pharmacology: Assessment of drug effects on cell morphology and toxicity evaluation.
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🧠 Neurology: Study of morphological changes in nerve cells linked to neurodegenerative diseases.
Tissue Biomarker Imaging
Map tissue biomarkers for in-depth analyses in pathology and clinical research.
Used to locate and quantify specific biomarkers in tissue samples, aiding in pathological diagnostics and disease research.
Key Benefits:
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🔬 Precise Visualization: Enables high-resolution spatial mapping of biomarkers within tissues, providing detailed images that reveal crucial localization insights.
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📊 Detailed Quantification: Offers precise biomarker quantification, facilitating accurate assessment of their concentration and distribution in tissue samples.
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🚀 Artifact Reduction: Laser scanning technology minimizes artifacts and background noise, enhancing data clarity and reliability.
Applications:
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🧬 Pathological Diagnostics: Accurate biomarker analysis for disease diagnosis and progression assessment.
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🎗️ Oncology Research: Identification and mapping of tumor biomarkers for a better understanding of cancer mechanisms and therapeutic targets.
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🛡️ Immunology Studies: Localization and quantification of biomarkers in tissues, supporting autoimmune disease and infection research.
Advanced Image Analysis
Advanced image analysis provides valuable insights by transforming complex visual data into actionable information.
Advantages:
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Utilization of specialized software such as Imaris, ImageJ, and QuPath for in-depth microscopic data analysis.
Applications:
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3D reconstructions, biomarker quantification, gene expression analysis, and cellular structure examination.
